看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies.
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, {. h" C# m# sCombination Feasibility according to preliminary data
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Bevacizumab + sorafenib Yes, reduced dose
' o1 Q* T* A# U# ]$ Q/ c0 eBevacizumab + sunitinib† No + [3 k8 Y# N& J* X A
Bevacizumab + temsirolimus Yes 8 {/ C+ G1 |3 Z
Bevacizumab + everolimus Yes ( v1 k6 [% |9 q9 @5 H: r" n
Sorafenib + sunitinib ? 4 p# Y5 S& e; G$ _
Sorafenib + temsirolimus Yes, reduced dose
: f t( B) Z4 k x+ LSorafenib + everolimus Yes, reduced dose 8 f9 ^" H- u0 B+ c3 |, m
Sunitinib + temsirolimus† No ! \6 W/ G6 J8 T" H* l+ Y- ~
Sunitinib + everolimus ?
" z5 O4 j2 g. e! TTemsirolimus + everolimus ?
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- c5 g6 T T9 c, a- i1 `& t†Led to US FDA warning.6 a: K- H6 c* p3 Y) T
?: As yet unattempted combination.1 G1 k6 j% l7 o( E7 d
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